Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid
- Creator: O'Donnell, Liza , Dagley, Laura F. , Curley, Michael , Darbey, Annalucia , O'Shaughnessy, Peter J. , Diemer, Thorsten , Pilatz, Adrian , Fietz, Daniela , Stanton, Peter G. , Smith, Lee B. , Rebourcet, Diane
- Resource Type: journal article
- Date: 2023
A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function
- Creator: Gannon, Anne-Louise , Darbey, Annalucia L. , Rebourcet, Diane , Chensee, Grace , Lawrence, Ben M. , O'Donnell, Liza , Kelso, Joanna , Reed, Natalie , Parameswaran, Shanmathi , Smith, Sarah , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells: LIFR Signalling in Leydig Cells
- Creator: Curley, Michael , Darbey, Annalucia , O'Donnell, Liza , Kilcoyne, Karen R. , Wilson, Kirsten , Mungall, Will , Rebourcet, Diane , Guo, Jingtao , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice
- Creator: Lawrence, Ben M. , O'Donnell, Liza , Smith, Lee B. , Rebourcet, Diane
- Resource Type: journal article
- Date: 2022
Sertoli cells as key drivers of testis function
- Creator: O'Donnell, Liza , Smith, Lee B. , Rebourcet, Diane
- Resource Type: journal article
- Date: 2022
Sperm-specific proteins: new implications for diagnostic development and cancer immunotherapy
- Creator: O'Donnell, Liza , Smith, Lee B. , Rebourcet, Diane
- Resource Type: journal article
- Date: 2022
Androgen receptor is dispensable for x-zone regression in the female adrenal but regulates post-partum corticosterone levels and protects cortex integrity
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, Ian J. , Jørgensen, Anne , Frederiksen, Hanne , Curley, Michael , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2021
Hyperprolactinemia in a male pituitary androgen receptor knockout mouse is associated with female-like lactotroph development
- Creator: O'Hara, Laura , Christian, Helen C. , Le Tissier, Paul , Smith, Lee B.
- Resource Type: journal article
- Date: 2021
Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells
- Creator: Sararols, Pauline , Stevant, Isabelle , Neirijnck, Yasmine , Rebourcet, Diane , Darbey, Annalucia , Curley, Michael K. , Kuhne, Francoise , Dermitzakis, Emmanouil , Smith, Lee B. , Nef, Serge
- Resource Type: journal article
- Date: 2021
Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men
- Creator: O'Donnell, Liza , Rebourcet, Diane , Hobbs, Robin M. , McLachlan, Robert I. , Webb, Andrew I. , Pilatz, Adrian , Diemer, Thorsten , Smith, Lee B. , Stanton, Peter G. , Dagley, Laura F. , Sgaier, Raouda , Infusini, Giuseppe , O'Shaughnessy, Peter J. , Chalmel, Frederic , Fietz, Daniela , Weidner, Wolfgang , Legrand, Julien M. D.
- Resource Type: journal article
- Date: 2021
A comparison of in vivo viral targeting systems identifies adeno-associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice
- Creator: Darbey, Annalcuia , Rebourcet, Diane , Curley, Michael , Kilcoyne, Karen , Jeffery, Nathan , Reed, Natalie , Milne, Laura , Roesl, Cornelia , Brown, Pamela , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
- Creator: Rebourcet, Diane , Mackay, Rosa , Darbey, Annalucia , Curley, Michael K. , Jørgensen, Anne , Frederiksen, Hanne , Mitchell, Rod T. , O'Shaughnessy, Peter J. , Nef, Serge , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Characterisation of a mural cell network in the murine pituitary gland
- Creator: O'Hara, Laura , Christian, Helen C. , Jeffery, Nathan , Le Tissier, Paul , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Exogenous gonadotrophin stimulation induces partial maturation of human sertoli cells in a testicular xenotransplantation model for fertility preservation
- Creator: Hutka, Marsida , Smith, Lee B. , Goossens, Ellen , Wallace, W. Hamish B. , Stukenborg, Jan-Bernd , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Fertility preservation in childhood cancer: endocrine activity in prepubertal human testis xenografts exposed to a pubertal hormone environment
- Creator: Hutka, Marsida , Kadam, Prashant , Van Saen, Dorien , Homer, Natalie Z. M. , Onofre, Jaime , Wallace, W. Hamish B. , Smith, Lee B. , Stukenborg, Jan-Bernd , Goossens, Ellen , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Reconstitution of rat fetal testis during the masculinisation programming window induces focal dysgenesis consistent with testicular dysgenesis syndrome
- Creator: Smart, Ellie , Macdonald, Joni , Smith, Lee B. , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging
- Creator: Curley, Michael , Milne, Laura , Smith, Sarah , Jørgensen, Anne , Frederiksen, Hanne , Hadoke, Patrick , Potter, Paul , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mitchell, Rod T. , Smith, Lee B. , Mason, J. Ian , Rebourcet, Diane , Smith, Sarah , Traveres, Adriana , Alcaide-Corral, Carlos Jose , Frederiksen, Hanne , Jorgensen, Anne , Milne, Laura
- Resource Type: journal article
- Date: 2019
Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis
- Creator: O'Shaughnessy, Peter J. , Mitchell, Rod T. , Monteiro, Ana , O'Hara, Laura , Cruickshanks, Lyndsey , Claahsen-van der Grinten, Hedi , Brown, Pamela , Abel, Margaret , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, J. Ian , Jørgensen, Anne , Frederiksen, Hanne , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2019